Hydroxychloroquine, Remdesivir and more: what the WHO anti Covid guidelines say

Here are the drugs not to be used (or used only in some patients) for the treatment of Covid-19 according to the WHO

A little more than a year after the Covid-19 pandemic, the first certainties for the treatment of the disease are consolidated. While the world is still looking for a dedicated treatment and while numerous experimental studies are underway to find a drug, the WHO issues guidelines on drugs not to be used in Covid-19 treatment. Or to be used only and exclusively in some cases.

HYDROXYCHLOROKINE

Not recommended, reports the Bjm , is the use of hydroxychloroquine, a drug marketed under the name of Plaquenil and used for the treatment of active and chronic rheumatoid arthritis and in discoid and disseminated lupus erythematosus.

LOPINAVIR-RITONAVIR

The pharmacological combination of lopinavir / ritonavir, HIV protease inhibitors, was also rejected.

REMDESIVIR

Remdesivir , marketed under the name of Veklury, should not be used in the treatment of Covid-19. It is a nucleotide prodrug used to treat Ebola virus disease and Marburg virus infections. Several studies have shown its effectiveness as an antiviral against single-stranded RNA viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, Nipah virus, Hendra virus, and Coronavirus (including MERS and SARS viruses).

CORTICOSTEROIDS

Corticosteroids, drugs that derive from cortisone and act by blocking the inflammatory process, should also be used, but with limitations. . The administration, according to a BMJ publication, is recommended only in patients who need oxygen therapy. In patients without the need for oxygen, corticosteroids can increase the risks.

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This is a machine translation from Italian language of a post published on Start Magazine at the URL https://www.startmag.it/sanita/idrossiclorochina-remdesivir-e-non-solo-che-cosa-dicono-le-linee-guida-oms-anti-covid/ on Sat, 08 May 2021 15:05:10 +0000.